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Furthermore, activation of the kynurenine pathway promotes the production of quinolinic acid, an excitotoxic compound that promotes glutamate release and blocks glutamate reuptake (Steiner et al., 2011

Nishida Y, Ishizawa J, Ayoub E, PatsilevasT, Ostermann LB, l Heinz Montoya R, Muftuoglu M, Ruvolo VR, Mak PY, Tao W, Carter BZ, Scruggs DA, Kojima K, Daver N, Lesegretain A, Seki T, Shacham S, Konopleva M, Andreeff M S

A randomized, double-blind phase I/IIa study of intranasal glutathione in Parkinsons disease

It has been shown that PL can selectively induce the death of head and neck cancer cells and increase cisplatin antitumor activity, involving the JNK and PARP death pathways [196]

10.1002/jbt.23354 167

peristaltic movements) [10, 11]
