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Remember, higher doses don't necessarily mean better results, especially with potentially toxic substances

Comparative Effects of berberine vs comparator in adults with obesity

Caffeine : Known for its stimulant effects, caffeine can improve endurance by reducing the perception of effort

Black SM, Field-Ridley A, Sharma S, Kumar S, Keller RL, Kameny R, et al

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On the other hand, similar intervention in combination with controlled hyperinsulinemia (~ 150mIU/L) elevates TC in skeletal muscle by ~ 15% [24, 25]