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[DOI] [PMC free article] [PubMed] [Google Scholar] 134.Li M.S., Adesina S.E., Ellis C.L., Gooch J.L., Hoover R.S., Williams C.R

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Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy

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Senescent mitochondria not only produce more ROS due to inefficient electron transport but also exhibit impaired iron-sulfur cluster biogenesis, leading to improper iron handling and accumulation within the mitochondria, thus creating a potent internal source of oxidative stress (106,107)
