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COL I and FN have opposite effects on melanin production and MC proliferation Given the observed role of ECM components for MC morphology and migration, we next investigated whether ECM cues influence other MC functions

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For example, in the high-fat and low-carbohydrate diet group, the phosphorylation of Ser307 significantly increased, while in the low-fat and high-carbohydrate diet group, it showed a decreasing trend (113)
