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64 Notably, cationic delivery strategies require careful design to support weak, reversible interactions with the cartilage matrix, because an excessively positive charge may favor tight binding, potentially limiting penetrability

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The UE velocity \({\varvec{V \) is assumed to vary from 30 to 150 km/hr, and the data packet arrival rate \({\varvec{\lambda \) is assumed to vary by these values 0.05, 00.1, 1, and 5 ms 1

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