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First, we used CMS4-derived organoids (from a patient with PM) in which the catalytic subunit of glutamate-cysteine ligase (GCLC) was deleted using CRISPR-CAS9 technology

10.1016/j.resp.2023.104202 Respir

Treating comorbidities ME/CFS displays an overlap with several autoimmune or immune-mediated diseases that also have chronic fatigue as a main symptom, such as Hashimotos thyroiditis (530), fibromyalgia (FM) (532, 554557), Mast Cell Activation Disorder (532), sleep apnoea (532), IBS (532), secondary depression or anxiety (532), Ehlers-Danlos syndrome (532), and PoTS (532, 558563)

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I went to a pharmacy where they gave me the injection and I was instructed to wait in the lobby for 15 minutes

These findings were strongly corroborated by the flow cytometry data, showing a consistent pattern of elevated FR levels in cancer cells compared to normal counterparts