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The severity of symptoms varies from person to person
VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release [J]

Gremeau-Richard, C

The death of dopamine-producing neurons in the substantia nigra causes Parkinsons disease.[ref] MPTP was discovered as a contaminant in illegal drugs that caused immediate and irreversible Parkinsons symptoms

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The translation of exceedingly assuring experiments in animals into clinical trials fails to keep pace
