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Reference Tuell JL, Bhattacharya D, Leeuwenburgh C, Chaudhuri A, Kumar V

Patients with whole gene deletion present with a very large neurofibroma burden, more severe cognitive impairment, large hands and feet, dysmorphic facial features, and have a higher lifetime risk of developing malignant peripheral nerve sheath tumors (MPNST) 27 , 28

If the 2 to 4 hour concentration is below 150 mg/L (1000 mol/L) acetylcysteine is not required