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From a functional point of view MOR phosphorylation following sciatic nerve ligature was correlated with desensitization of receptor ability to stimulate the G protein, development of cyclase superactivation, appearance of thermal hyperalgesia and reduced analgesic response to exogenous opioids [10, 76]

DAUGAARD, G., HOLSTEIN-RATHLOU, N.-H., & LEYSSAC, P.P

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