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795 FEACR overexpression inhibits I/R-induced ferroptosis and myocardial infarction through SIRT1-forkhead box O1 (FOXO1)-FTH1 pathway, improving cardiac function
Therefore, the FOXO1-C/EBP-ATF4 axis not only directly drives proteolysis through the ubiquitin-proteasome system but also indirectly supports these processes by elevating stress response genes like ChaC1 (Oyabu et al., 2022
These sources can interact, with the activity of one enhancing the function of the others [51,52,53]
