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10.1016/j.joca.2021.01.011

In addition, we performed immunofluorescence colocalization analysis to examine the expression levels of pyroptosis biomarkers NLRP3 and ASC in macrophages expressing the C38S mutant and wildtype p65

3.1.4 Regulate Treg/Th17 balance and reconstruct immune tolerance The imbalance of Treg/Th17 cells is central to the abnormal adaptive immunity in IBD

Clin Cancer Res 6(7):27352740 Ijichi H et al (2011) Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma

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Key strategies include consuming a diet rich in cruciferous vegetables, maintaining adequate hydration, and using supplements like milk thistle, N-acetylcysteine (NAC), and glutathione