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While staying hydrated by drinking enough water is essential, many people find it hard to meet adequate water intake during the day

10.1016/j.pnpbp.2021.110405 20 BrownH

Although not a direct drug-drug interaction, increased GH/IGF-1 levels may raise blood glucose

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Safety Profile and Potential Side Effects Reported Adverse Effects Animal studies report minimal toxicity even at high doses

First, subjects were judged as exhibiting the diabetic type if they met one of the following criteria: (1) fasting plasma glucose level of 126 mg/dL ( 7.0 mmol/L), (2) 2-h value of 200 mg/dL ( 11.1 mmol/L) on 75 g oral glucose tolerance test (OGTT), (3) casual plasma glucose level of 200 mg/dL ( 11.1 mmol/L), or (4) hemoglobin A1c (HbA1c) based on the national glycohemoglobin standardization program 6.5%