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In studies as early as 2006, it was noted that curcumin was able to inhibit nuclear factor-kappa B-induced vascular endothelial growth factor expression, which led to a reduction in angiogenesis (Yoysungnoen et al., 2006)

Flupirtine at 100 mg also evoked comparable efficacy to paracetamol at 1g in treating acute episodic tension-type headache or acute attacks of migraine

We propose that data obtained from the experiments with M

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it also supports cellular uptake

However, due to the crystallinity nature, high lipophilicity, and low water solubility of kojic dipalmitate, its incorporations within the topical formulations would be more challenging (Zilles et al., 2023)