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In diseases such as HIV, Th2 predominance is a critical component of immune response and thus, GSH levels in antigen presenting cells may play an integral role in determining disease progression [29]

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In experiments involving histology and immunohistochemistry, the illustrations represent the outcomes of at least three independent experiments

doi: 10.1126/sciadv.1500447 40 OgiwaraHTakahashiKSasakiMKurodaTYoshidaHWatanabeRet al

Downregulation of GS is not due to protein degradation but rather the inhibition of protein synthesis Since NH 4 Cl has previously been reported to induce autophagy in mouse embryo fibroblasts and tumor cells 17,18,19 , we wondered if GS downregulation in astrocytes upon glutamate and NH 4 Cl co-treatment was due to protein degradation

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