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Keywords: exercise training, nutraceuticals, flavonoids intake, aging, antioxidant supplementation INTRODUCTION Free radicals are generated during normal cellular function and are part of the natural physiological process of all living beings [13]

Removing the impaired mitochondria and replenishing healthy mitochondria are promising therapeutic approaches to treat hypoxia/ischemia related diseases, especially in CNS which mitochondria are abundance in the distal axonal synapses and dendritic protrusions [110-112]

It is a natural hormone that primarily functions to increase appetite and stimulate the secretion of growth hormone

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