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In addition, metabolic abnormalities due to specific, inherited enzyme deficiencies can affect the liver

doi: 10.1111/j.1530-0277.1995.tb01586.x

To overcome the difficulties in targeting NRF2 for controlling NRF2-addicted cancers, targeting metabolic liabilities unique to NRF2-addicted cancer cells, such as dependency on exogenous NEAAs, including glutamine, is a very sensible way to achieve selective toxicity toward cancers that have fallen in NRF2 addiction

doi:10.1016/b978-008055232-3.60034-0

and Infect

Estimates of the relative contributions of heritability and environmental factors are influenced by varying assumptions of autism prevalence, among other factors, and more research is needed to generate more precise estimates
