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Askari B S, Krajinovic M (2010) Dihydrofolate reductase gene variations in susceptibility to disease and treatment outcomes
On the other hand, MTI-101 is a promising CD44-binding peptidomimetic (a cyclized peptidomimetic derivative of HYD1) that induces necroptosis in MM cells through mechanisms involving oxidative stress, mitochondrial dysfunction, and necroptosis-like signaling, demonstrating efficacy even within the bone marrow microenvironment (30)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 104.Ndagijimana M., Laghi L., Vitali B., Placucci G., Brigidi P., Guerzoni E
Very interesting work was also done by the group of Albert et al
10.1109/embc.2018.8512784 41 ChenM.ZhuJ.KangJ.LaiX.GaoY.GanH.et al (2019a)
