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Show details CASRN: 541-15-1
doi: 10.1111/1541-4337.12342

Fernandez, M
253 Brodalumab was approved for the treatment of moderate-to-severe plaque psoriasis by the Japanese Pharmaceuticals and Medical Devices Agency in July 2016 (Lumicef), FDA in February 2017 (SiliqTM), and European Medicines Agency in July 2017 (Kyntheum)

The strongest body-weight meta-analysis found a modest average reduction of about 1.21 kg, with the best dose-response signal near 2,000 mg/day, mostly in adults with overweight or obesity

At last, a role for MAPK activation in muscle protein synthesis and cachectic or sarcopenic conditions has been reported [119]
