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The effects of human GH and its lipolytic fragment (AOD 9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice

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The dual mechanism was confirmed at the cellular level, and the fragment showed no cross-reactivity with the growth hormone receptor (Ng & Borstein, 2003)

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AOD9604 stimulates lipolysis (the breakdown or destruction of fat) and inhibits lipogenesis in animal studies

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