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Glob J Health Sci

In addition, the p62-Keap1-NRF2 32 , ATG5-ATG7-NCOA4 33 , and glutamine metabolic pathways 25 can effectively regulate the formation of intracellular iron ions and ROS and play a regulatory role in ferroptosis (Fig

Jungsuwadee P, Cole MP, Sultana R, Joshi G, Tangpong J, Butterfield DA, et al

(4) increased hepatic and renal urea cycle intermediates suggesting hypercatabolism and upregulation of the urea cycle independent of impaired renal clearance of nitrogenous waste

The oxidized form, GSSG, can be reduced back to reduced glutathione with the help of glutathione reductase ( GSR gene ) and NADPH

Ough, M
