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Some preclinical data suggests BPC-157 demonstrates oral bioavailability, but direct comparisons between injectable study protocols and oral supplementation in humans have not been established through clinical research

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In the early 1980s, NMDA receptors were shown to be involved in several central synaptic pathways

Therefore in many organs, neuropeptides can exert effects through direct innervation of the end organ (synaptic contact), but also through non-synaptic contact and paracrine activity on neighboring cells [21]