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Description
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

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4.1 Limitations and implications for practice This meta-analysis has several limitations that should be considered when interpreting the findings

Insulin-like growth factors

Clinicians typically start patients at the middle ODT dose (5 mg) when switching from low-dose injectables (0.25 to 0.5 mg weekly) and titrate based on response

The dose needed depends on how severe the deficiency is and what each person needs
