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10.1016/j.bbagen.2012.05.016 [DOI] [PubMed] [Google Scholar] Kipp A

Histopathological analyses have demonstrated that the chronic constriction injury (CCI) model is typified by nerve fiber demyelination, axonal degeneration, and a decrease in A fibers (45, 47), while the majority of C-fibers remain relatively intact, and this specific injury pattern is closely associated with mechanical and thermal nociceptive sensitization in neuropathic pain (46)

This may lead to potential issues with the psychiatrist challenging the diagnosis, including reports of no clear psychiatric diagnosis being found (64)