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Another small molecule, AMG 337, which is a selective inhibitor targeting c-Met has also been reported (Van Cutsem et al., 2019)

In doxorubicin (DOX)-induced cardiomyopathy models, SIRT1 downregulation exacerbates ferroptosis in cardiomyocytes, while its activation reduces oxidative stress and inhibits ferroptosis by increasing the expression of antioxidant enzymes such as GPX4

"Perspective: Practical Approach to Preventing Subclinical B12 Deficiency in Elderly Population"

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