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Whereas, large sized AuNPs (60 nm size) are reported to have higher accumulation in spleen [320]

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Therefore, future research can focus on developing safer and more effective antiplatelet drugs or treatment strategies, exploring the combined application of antiplatelet drugs with other drugs, and utilizing advanced technologies such as genomics to achieve precise treatment for patients

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This process is also marked by the expression of the senescence-associated secretory phenotype (SASP), which bridges cellular senescence with tissue dysfunction and organismal aging (31)