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An optimized exosome production strategy for enhanced yield while without sacrificing cargo loading efficiency

Ejerce una accin protectora y reparadora del dao celular previniendo el envejecimiento cutneo

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J Cancer 14(16):29562963

Results We demonstrated that this peptide-liposome-small molecule machinery targets AML and consequently induces cell apoptosis both in vitro and in vivo through three disparate mechanisms: (I) Oridonin, as a Michael acceptor molecule, inhibits GSH function through covalent bonding, triggering an initial imbalance of oxidative stress

A more accurate assessment of these values was not possible due to low solubility of these compounds at high micromolar concentrations