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L-carnitine mightnt have the sports nutrition ubiquity of whey powder or caffeine in the endurance sports world, but it is probably in the top-10 of performance-enhancing food supplements in terms of science backing

Nuzzo says abruptly stopping L-carnitine supplementation may cause temporary withdrawal effects such as fatigue, muscle cramping, irritability, or gastrointestinal symptoms

[20] In the brainstem acetylcholine originates from the Pedunculopontine nucleus and laterodorsal tegmental nucleus collectively known as the mesopontine tegmentum area or pontomesencephalotegmental complex

When injected into the muscle or taken by mouth, acetyl-L-carnitine appears to reduce some symptoms of fibromyalgia

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Half of the participants received the active treatment, while the other half received a placebo