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In this Review, we describe and summarize the key features of direct thyroid hormone regulation of lipogenesis, fatty acid -oxidation, cholesterol synthesis and the reverse cholesterol transport pathway in normal and altered thyroid hormone states

Nov 30;61(14):1332-1342

At 600 mg/day, Coluzzi says, There are no side effects. However, double this dose is often used, which occasionally causes mild gastrointestinal irritation

Its role in fatty-acid oxidation is well established in basic science, and its been used clinically for decades in settings where mitochondrial function needs explicit support

However, another study found that free carnitine was decreased in depression group (32)