glutathione vitamim e interaction On the Potential Role of the Antioxidant Couple Vitamin E/Selenium Taken by the Oral Route in Skin and Hair Health Vitamin E–drug interactions: molecular basis

Challenges and limitations Despite its promising therapeutic potential, curcumin exhibits poor aqueous solubility (11 ng/mL), chemical instability at neutral to alkaline pH, and low oral bioavailability due to rapid hepatic metabolism and systemic elimination

14-3-3 plays a role in cardiac ventricular compaction by regulating the cardiomyocyte cell cycle

Wickens et al., 2007

4.3 Sorafenib Sorafenib has been shown to have inhibitory effects against platelet-derived growth factor receptor (PDGFR), VEGFR2, VEGFR-3, PDGFR- and other receptors (135)

Its epigenetic modulation capabilities also suggest it can influence DNA methylation patterns and histone modifications, potentially providing long-term regulatory mechanisms for inflammatory processes [44]

Liu SZ, Tan XY, Liu T, Ke J, Zou FY, Jia BY, et al