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While ROS generation is modest during the ischemic phase due to oxygen deprivation (Sen et al., 2024), a substantial and rapid burst occurs upon the sudden reintroduction of oxygen during reperfusion (Xiang et al., 2021

[DOI] [PubMed] [Google Scholar] 27.Falnes P., Maecki J.M., Herrera M.C., Bengtsen M., Davydova E

B.BowenR

However, activity spontaneously recovered suggesting that thioredoxin was able to de-glutathionylate itself

Chuang PH, Lee CW, Chou JY, Murugan M, Shieh BJ, Chen HM
346 Nitroalkenes can also be precursors of other nitrated species because they can undergo additional reactions with ROS and RNS to be further nitrated, and form nitroso, dinitroso, nitronitroso, di- and trinitro species
