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Under the favor of combination of the structure-based design and combinatorial chemistry, the efforts to synthesis a convenient structure are minimized [9]

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Samples were stored at 20 C, for no longer than 6 months prior to analysis

93,187 In the cytosol, instead, they rely on an HSP70-centric system: HSP70 (HSPA1A in humans), HSP110 (HSPH1 in humans, a nucleotide exchange factor/NEF), and J-proteins (DNAJA2, DNAJB1 in humans) collaborate to extract and refold aggregated proteins (Fig

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