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Its not a failure

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1.2.3 Supply issues and environmental sustainability According to a recent market analysis report by Mordor Intelligence, global FBS market is valued at $2.35 billion in 2025 and is projected to reach $4.62 billion by 2030, representing a compound annual growth rate of 14.5%, though estimates vary across forecasting firms (Mordor Intelligence, 2025)

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Expression and purification of full-length mouse CARM1 from transiently transfected HEK293T cells using HaloTag technology
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doi:10.1016/j.hepres.2005.12.005