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In the NEJM Phase 2 trial, participants assigned to an initial dose of 4 mg experienced significantly more adverse events than those who started at 2 mg, even when both groups ultimately reached the same target dose

Taking in extra B12 through injections or supplements when your levels are already normal will not provide additional benefits

Ice crystal formation disrupts the peptides structure, and repeated freeze-thaw cycles have been observed to reduce biological activity by 20-50% (2)

Using it for a multi-dose vial is asking for bacterial growth in a protein-rich solution

and C.C

Inject a couple milliliters of air into the vial