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Khodakarami, H., Shokouhi, N

PMCID: PMC3584306

Patients with Leber's Disease: Vitamin B12 levels may exacerbate optic nerve atrophy

Overall, mounting evidence suggests that targeting CD38 and related NAD + -consuming enzymes, such as PARPs, has great potential as an NAD + -boosting target to extend human healthspan, and several pharmacological approaches are in development to inhibit CD38 and its NADase activity 232 (TABLE 1)

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Gastroenterology 123 , 16071615 (2002)
