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Under homeostatic conditions, the deubiquitinase PSMD14 cleaves K27-linked polyubiquitin chains at K313 of IRF3, thereby preventing autophagic recognition and degradation (193)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 2.Shanina E, Liao B, Smith RG

Impaired DNA synthesis represents the primary mechanism