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Its importance has led to the development of various anti-CD38 monoclonal antibodies (mAbs), including daratumumab and isatuximab, approved for MM treatment

Some symptoms of chronic inflammation are discomfort on the joints, liver cirrhosis, chronic pain, asthma and rheumatoid arthritis

The substantial upregulation of FAP is considered a biomarker for CAFs [33, 34], with potential as a unfavourable prognosis biomarker for various cancers [35,36,37,38]

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BMJ 366
