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OSullivan D, van der Windt GJ, Huang SC, Curtis JD, Chang CH, Buck MD, et al
PubMed 39161060

In mammalian models, exposure has been reported as concentrations in drinking water (e.g., 0.550 g/mL for 90 days) [134] and as oral doses spanning from mg/kg/day regimens to very high bolus doses (e.g., up to 2000 mg/kg by gavage) [141]

In pro-oxidant conditions, two GSH molecules dimerize through a disulfide bond to form GSSG, whereas in antioxidant conditions GSSG is converted to GSH via NADPH-dependent glutathione reductase, as depicted in Figure 1 [2]
