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A short account is devoted to the detoxification of heavy metals by chelation via the use of ethylenediaminetetraacetic acid (EDTA), dimercaprol (BAL), 2,3-dimercaptosuccinic acid (DMSA), 2,3-dimercapto-1-propane sulfonic acid (DMPS), and penicillamine chelators.

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The injections are typically administered intramuscularly and are known to provide quicker relief from symptoms of B12 deficiency compared to oral supplements

The copper component of GHK-Cu contributes directly to angiogenic processes by serving as an essential cofactor for lysyl oxidase and other enzymes involved in ECM cross-linking required for vessel maturation and stability