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Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines

Activation of Pro-uPA is critical for initial escape from the primary tumor and hematogenous dissemination of human carcinoma cells
On the other hand, although G6PD expression is significantly reduced under hypoxic conditions and reversed by the proteasome inhibitor MG132, the specific mechanism remains unclear (Chettimada et al., 2015)

10.1016/j.advms.2020.06.004 28 BrownC

Clin Perinatol 14 : 651666 Turrens JF, Freeman BA, Crapo JD 1982 Hyperoxia increases H2O2release by lung mitochondria and microsomes

Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice
