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Table 7

Recognizing the signs, from persistent fatigue and brain fog to mood changes and tingling, is the first step, and a simple blood test can confirm whether B12 is the cause

Nature Medicine, 30(7), 2049-2057

This has profound downstream effects, including boosting cellular metabolism, promoting fat breakdown (lipolysis), and reducing the accumulation of adipose tissue in preclinical models

Other symptoms of vitamin B12 deficiency include problems with balance, depression, confusion, dementia, poor memory, and soreness of the mouth or tongue

The SURMOUNT-1 trial of tirzepatide reported 4.3-7.1% across dose groups