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The production of H 2 S n , Cys-SS n H and GSS n H was greatly decreased in C247S and R187G as predicted from the result that cysteine and GSH were not consumed by both mutants (Fig

& Schorah, C

This contrasts with its role in pulmonary fibrosis, where its primary cellular targets are likely activated fibroblasts and alveolar epithelial cells, highlighting how curcumins efficacy is shaped by the unique cellular ecosystem of each diseased organ

Mol Psychiatry 251(25):131147
2006;147(Suppl 1):S193S201

Under conditions of high succinate concentrations, complex II induces the entry of electrons into complex I through a process known as reverse electron transfer, resulting in the generation of ROS
