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Common side effects are typically mild and transient: Pain, redness, or swelling at the injection site (most frequent) Mild diarrhoea or gastrointestinal upset Headache or dizziness shortly after administration Itching or mild skin reactions Temporary pink/red discolouration of urine These effects usually resolve within 2448 hours without intervention
Free Radic Biol Med (2020) 147:13949
Some practitioners recommend starting Retatrutide first, allowing the body to adapt to its effects over four to six weeks before adding Sermorelin
the second may be due to stimulation of the degradation of BACE1/APP to reduce A levels in the brain
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