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Therefore, without time stamping, the authors postulate that circadian rhythms and memory formation could become disrupted, as in AD

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The metabolism of peptides and proteins usually starts from the action of endopeptidase and then undergoes multi-step enzymatic degradation to produce the final metabolite amino acids, which enter the amino acid pool in vivo (Vugmeyster et al., 2012)

The inhibition of specific HDAC isoforms has shown therapeutic promise in AD models, improving cognitive function and reducing pathological hallmarks 30

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