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Long-term 3D PureCol EZ Gel (Fujii medium) Ileum (N39) organoids were cultured in expansion medium consisting of DMEM/F12 supplemented with 100 U ml 1 P/S, 10 mM HEPES, 1 Glutamax, 2% B-27 with VitA, 3% (v/v) recombinant R-spondin-3, 2% (v/v) recombinant noggin, 1 mM N -acetylcysteine, 0.5 nM Wnt surrogate, 0.1 g ml 1 hIGF-1 (Peprotech), 0.05 g ml 1 hFGF2 (Peprotech), 10 nM gastrin, 0.5 M A83-01, 0.05 g ml 1 hEGF, 3 M CHIR 99021 and 10 M forskolin (Tocris) 42

However, in COPD, increased oxidative stress leads to excessive mtROS production, inducing oxidative stress, abnormal mitophagy, and mitochondrial dysfunction (Fan et al., 2023)

In addition to insulin resistance, obesity (and intraorgan adipose tissue), poor-quality high-calorie diets, and lack of physical exercise are major risk factors for T2D [26]

doi: 10.5194/essd-16-2789-2024 Summary Keywords abiotic stress and crop resilience, and stomatal regulation, atmospheric gaseous pollutants, photosynthesis, plant biochemical stress responses, pollutant plant interactions, reactive oxygen and nitrogen species (ROS, RNS), respiration Citation Urfa Gul M, Gul MJ, Raza Ur Rehman MH, Choi GS and Park C-H (2026) Plant responses to gaseous pollutants, biochemical and transcriptomic insights

From SARS and MERS to COVID-19: a brief summary and comparison of severe acute respiratory infections caused by three highly pathogenic human coronaviruses

Environmental Protectional Agency