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Its now a growing problem among the young population, withy studies suggesting almost half of the entire American nation may be affected by B12 deficiency

Follow-up labs usually confirm resolution within a few months, though patients with recurring symptoms may eventually switch to methylcobalamin for its additional cellular benefits

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Regarding the SEV group, B12-upregulated genes had GO annotations related to cytoplasmic translation (tRNA and rRNA processing), adaptive immune response, ncRNA processing, miRNA-mediated gene silencing, proteasome-mediated ubiquitin-dependent protein catabolic process, cobalamin transport, and negative regulation of transcription by RNA polymerase II ( Figure S3 )

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