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This condition may depend on the type 2 polarization, diminishing type 1 immunity devoted to fighting infections, ICAM-1 overexpression on epithelial cells (ICAM-1 is the primary receptor for rhinoviruses), and chronic inflammation that promotes microbial rooting [89]

Lei W, Luo Y, Lei W, Luo Y, Yan K, Zhao S, Li Y, Qiu X, Zhou Y, Long H (2009) Abnormal DNA methylation in CD4+ T cells from patients with systemic lupus erythematosus, systemic sclerosis, and dermatomyositis

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Tangeretin Polymethoxylated flavone (PMF) tangeretin is mostly present in citrus peels

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