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If it was exposed to higher temperatures or exceeded 28 days unrefrigerated, it should be discarded

Introduction With high and rising rates of adiposity and related morbidity, mortality, and healthcare expenditures, recently approved glucagon-like peptide 1 receptor agonists and related combination obesity medications (collectively referred to as GLP-1s1) are shifting the treatment landscape shifting the treatment landscape (we collectively refer to these as GLP-1s given this common practical usage by clinicians, policymakers, and the public

Further advantages (see Box 2 ) have led the American Diabetes Association (ADA) to recommend incretin mimetics as the first-choice injectable glucose-lowering therapy for type 2 diabetes, ahead of insulin (ADA, 2026)

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When to Contact Your Healthcare Team Seek immediate help if you experience new or worsening seizures, severe dizziness, confusion, or loss of consciousness after starting semaglutide