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Patients received one of the following treatments: sitagliptin 50 mg twice daily plus metformin 1,000 mg twice daily sitagliptin 50 mg twice daily plus metformin 500 mg twice daily metformin 1,000 mg twice daily metformin 500 mg twice daily sitagliptin 100 mg daily placebo (from weeks 1 to 24) Patients who had initially received placebo were switched to metformin 1,000 mg twice daily at week 24

The difference between brand-name and compounded GLP-1 therapy is primarily economic and logistical, not clinical

[DOI] [PMC free article] [PubMed] [Google Scholar] 15.Spring B, Duncan JM, Janke EA, Kozak AT, McFadden HG, DeMott A, Pictor A, Epstein LH, Siddique J, Pellegrini CA, Buscemi J, Hedeker D

Heppner KM, Perez-Tilve D

Important safety information: This calculator estimates a starting daily calorie target

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