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In ATTAIN-MAINTAIN, patients who had plateaued after injectable therapy switched to oral orforglipron, marketed as Foundayo

Incretin medicines work through hormone pathways that affect appetite, glucose-dependent insulin release, stomach emptying, and metabolic signaling

[DOI] [PMC free article] [PubMed] [Google Scholar] [97].Fineman M, Flanagan S, Taylor K, Aisporna M, Shen LZ, Mace KF, Walsh B, Diamant M, Cirincione B, Kothare P, Li WI, MacConell L, Pharmacokinetics and pharmacodynamics of exenatide extended-release after single and multiple dosing, Clinical pharmacokinetics, 50 (2011) 6574

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Doctors must demonstrate that enrollees are losing weight every six months to renew their prescription