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26,27 A Phase II trial in T2D showed a 1% reduction in HbA1c (Diabetes Control and Complications Trial units) and approximately 1.7% body weight reduction over 12 weeks, in comparison to placebo, but a further comparison to an open-label liraglutide active treatment control group was less impressive

Y., Zhang, H
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3.1.3 Dulaglutide: marginal gains within the context of lifestyle intervention The key finding regarding dulaglutide is that the incremental benefit of the drug diminishes when the control group is already engaged in a structured calorie-restricted diet (CRD)

J Bioenerg Biomembr 47: 409-417